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A descriptive analysis of pediatric post-tonsillectomy pain and recovery outcomes over a 10-day recovery period from 2 randomized controlled trials

机译:2项随机对照试验对10个月恢复期内小儿扁桃体切除术后的疼痛和恢复结果进行描述性分析

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摘要

Pediatric tonsillectomy involves an often painful and lengthy recovery period, yet the extended recovery process is largely unknown. This article describes postoperative recovery outcomes for 121 children aged 4 to 15 (mean 6.6 years, SD = 2.3) years enrolled in 1 of 2 clinical trials of analgesia safety and efficacy after tonsillectomy. Postoperative analgesia included scheduled opioid analgesic plus acetaminophen/ibuprofen medication use (first 5 days) and “as-needed” use (last 5 days). Clinical recovery as measured daily by the Parents' Postoperative Pain Measure (PPPM; an observational/behavioral pain measure), children's self-reported pain scores, side-effect assessments, need for unanticipated medical care, and satisfaction with recovery over 10 days was assessed. Higher Parents' Postoperative Pain Measure scores were correlated with poorer sleep, receipt of breakthrough analgesics, distressing side effects, higher self-reported pain scores, and need for unanticipated medical care. Higher self-reported pain scores were associated with more distressing adverse events, including nausea, vomiting, insomnia, lower parent satisfaction, and unplanned medical visits and hospitalizations. Pain and symptoms improved over time, although 24% of the children were still experiencing clinically significant pain on day 10. Scheduled, multimodal analgesia and discharge education that sets realistic expectations is important. This study adds to the emerging body of literature that some children experience significant postoperative pain for an extended period after tonsillectomy.
机译:小儿扁桃体切除术通常涉及痛苦且漫长的恢复期,但是延长恢复过程在很大程度上尚不清楚。本文介绍了参加2项扁桃体切除术后镇痛安全性和有效性的临床试验之一的121例4至15岁(平均6.6岁,SD = 2.3)岁的儿童的术后恢复结果。术后镇痛包括计划的阿片类镇痛加对乙酰氨基酚/布洛芬用药(头5天)和“按需”使用(后5天)。评估每天的临床康复情况,包括父母术后疼痛评估(PPPM;观察/行为疼痛评估),儿童自我报告的疼痛评分,副作用评估,需要的医疗服务以及对10天康复的满意程度。高父母的术后疼痛评估得分与睡眠差,突破性镇痛药的接受,令人痛苦的副作用,自我报告的疼痛得分更高以及需要意外医疗有关。自我报告的疼痛评分较高与更令人痛苦的不良事件相关,包括恶心,呕吐,失眠,父母满意度降低以及计划外的就诊和住院治疗。疼痛和症状会随着时间的推移而改善,尽管24%的儿童在第10天仍在临床上遭受明显的疼痛,因此,制定切合实际的期望的定期多模式镇痛和出院教育非常重要。这项研究增加了新兴的文献资料,即一些儿童在扁桃体切除术后的较长时间内会出现明显的术后疼痛。

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