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Neuro-oncologists have spoken – the role of bevacizumab in the inpatient setting. A clinical and economic conundrum

机译:神经肿瘤学家已经发表了讲话–贝伐单抗在住院患者中的作用。临床和经济难题

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摘要

Bevacizumab is a monoclonal antibody targeting vascular endothelial growth factor (VEGF), a key player in tumor angiogenesis. The drug can halt tumor progression, treat radiation necrosis, and reduce peritumoral edema. Although it does not increase overall survival, bevacizumab can improve progression-free survival and quality of life. In many countries, bevacizumab use in the inpatient setting is restricted due to its significant cost. Here, we explore attitudes towards the use of bevacizumab amidst practitioners treating brain tumors and assess ease of accessing the drug in the inpatient setting.
机译:贝伐单抗是靶向血管内皮生长因子(VEGF)的单克隆抗体,VEGF是肿瘤血管生成的关键角色。该药物可以阻止肿瘤进展,治疗放射坏死并减轻肿瘤周围水肿。贝伐单抗虽然不会增加总生存期,但可以改善无进展生存期和生活质量。在许多国家,贝伐珠单抗在住院患者中的使用因成本高昂而受到限制。在这里,我们探讨在治疗脑部肿瘤的医生中使用贝伐单抗的态度,并评估在住院环境中使用该药物的难易程度。

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