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Unrecognized HIV infection in asymptomatic volunteer blood donors at district Peshawar Khyber Pakhtunkhwa Pakistan

机译:巴基斯坦开伯尔-普赫图赫瓦省白沙瓦地区无症状的无偿献血者中未被识别的艾滋病毒感染

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摘要

Acquired immunodeficiency syndrome (AIDS) is a global epidemic that impacts the lives of many individuals each year. Human immunodeficiency virus (HIV) is a retrovirus that infects human CD4 T helper cells and macrophages thereby causing severe immune disease. The current study aimed to examine the prevalence of HIV among the blood donors of Khyber Pakhtunkhwa at Peshawar. In this study, a total of 8634 volunteers who donated blood were carefully screened for HIV using ELISA and RT-PCR techniques. Among the volunteers (  = 8634), 63 were positive by both ELISA and RT-PCR; which shows a prevalence of 0.73%. Both diagnostic techniques exhibited similar results. All the positive individuals were informed immediately and advised to start treatment to control the progression of the infection. It was concluded that HIV is on the rise in Peshawar, and routine screening and preventive measures are immediately required to address the urgent situation of HIV infection.
机译:后天免疫机能丧失综合症(AIDS)是全球性流行病,每年都会影响许多人的生活。人类免疫缺陷病毒(HIV)是一种逆转录病毒,可感染人类CD4 T辅助细胞和巨噬细胞,从而引起严重的免疫疾病。目前的研究旨在检查白沙瓦开伯尔·普赫图赫瓦省献血者中艾滋病毒的流行。在这项研究中,使用ELISA和RT-PCR技术仔细筛选了8634名献血志愿者。在志愿者(= 8634)中,ELISA和RT-PCR均为63阳性;患病率为0.73%。两种诊断技术均显示出相似的结果。立即告知所有阳性个体,并建议他们开始治疗以控制感染的进程。可以得出结论,白沙瓦的艾滋病毒正在增加,必须立即采取常规筛查和预防措施,以解决艾滋病毒感染的紧急情况。

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