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Managing Functional Neurological Disorders: Protocol of a Cohort Study on Psychogenic Non-Epileptic Seizures Study

机译:管理功能性神经疾病:心因性非癫痫性癫痫研究队列研究的方案

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摘要

Functional neurological disorders (FNDs) are neurological symptoms that cannot be explained by an underlying neurological lesion or other medical illness and that do not have clear neuropathological correlates. Psychogenic non-epileptic seizures (PNES) are a common and highly disabling form of FND, characterized by paroxysmal episodes of involuntary movements and altered consciousness that can appear clinically similar to epileptic seizures. PNES are unique among FNDs in that they are diagnosed by video electroencephalographic (VEEG), a well-established biomarker for the disorder. The course of illness and response to treatment of PNES remain controversial. This study aims to describe the epidemiology of PNES in the Department of Veterans Affairs Healthcare System (VA), evaluate outcomes of veterans offered different treatments, and compare models of care for PNES.
机译:功能性神经疾病(FND)是无法由潜在的神经病变或其他医学疾病解释的神经症状,并且没有明确的神经病理学相关性。心因性非癫痫性癫痫发作(PNES)是FND的一种常见且高度致残的形式,其特征是发作性不自主运动和意识改变,在临床上可能类似于癫痫性发作。 PNES在FND中是独特的,因为它们可以通过视频脑电图(VEEG)进行诊断,而视频脑电图是该疾病公认的生物标志物。病程和对PNES的治疗反应仍然存在争议。本研究旨在描述退伍军人事务医疗系统部(VA)的PNES流行病学,评估提供不同治疗方法的退伍军人的结局,并比较PNES的护理模式。

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