Fluoxetine is Neuroprotective in Early Brain Injury via its Anti-inflammatory and Anti-apoptotic Effects in a Rat Experimental Subarachnoid Hemorrhage Model

摘要

Fluoxetine treatment ameliorates the neurological deficit and brain edema after SAH. Left: representative images of sham, SAH + vehicle, SAH + fluoxetine rat brains 72 h after surgery. Right: the SAH scores showed no significant difference between the SAH + vehicle and SAH + fluoxetine groups, =10/group. and Effects of fluoxetine on ( ) neurological score (48 and 72 h) and ( ) brain water content (72 h) following SAH (mean ± SEM, = 6/group; one-way ANOVA followed by Turkey’s test).