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Surface Treatment of Acetabular Cups with a Direct Deposition of a Composite Nanostructured Layer Using a High Electrostatic Field

机译:通过使用高静电场直接沉积复合纳米结构层对髋臼杯进行表面处理

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摘要

A composite nanofibrous layer containing collagen and hydroxyapatite was deposited on selected surface areas of titanium acetabular cups. The layer was deposited on the irregular surface of these 3D objects using a specially developed electrospinning system designed to ensure the stability of the spinning process and to produce a layer approximately 100 micrometers thick with an adequate thickness uniformity. It was verified that the layer had the intended nanostructured morphology throughout its entire thickness and that the prepared layer sufficiently adhered to the smooth surface of the model titanium implants even after all the post-deposition sterilization and stabilization treatments were performed. The resulting layers had an average thickness of (110 ± 30) micrometers and an average fiber diameter of (170 ± 49) nanometers. They were produced using a relatively simple and cost-effective technology and yet they were verifiably biocompatible and structurally stable. Collagen- and hydroxyapatite-based composite nanostructured surface modifications represent promising surface treatment options for metal implants.
机译:包含胶原蛋白和羟基磷灰石的复合纳米纤维层沉积在髋臼杯的选定表面区域。使用专门开发的电纺丝系统将该层沉积在这些3D对象的不规则表面上,该系统设计为确保纺丝过程的稳定性并生产出厚度约为100微米且具有足够厚度均匀性的层。证实了该层在其整个厚度上均具有预期的纳米结构形态,并且即使在进行了所有沉积后灭菌和稳定化处理之后,所制备的层也充分粘附至模型钛植​​入物的光滑表面。所得层的平均厚度为(110±30)微米,平均纤维直径为(170±49)纳米。它们是使用相对简单且具有成本效益的技术生产的,但它们具有可生物相容性和结构稳定性。基于胶原蛋白和羟基磷灰石的复合纳米结构表面修饰代表了金属植入物的有前途的表面处理选择。

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