Testicular Cancer as a Model for Understanding the Impact of Evolving Treatment Strategies on the Long-Term Health of Cancer Survivors

摘要

Over the last century, radiotherapy has been used successfully to treat early stage testicular cancer, particularly seminomas. With the development of cisplatin-based chemotherapy regimens in the 1970s for advanced disease and nonseminomas, testicular cancer became one of the most curable malignancies and a defining achievement in oncology ( ). This favorable prognosis combined with the relatively young age at testicular cancer diagnosis have made the long-term health of survivors a high clinical and research priority as well as a driving force behind further treatment refinements.