Comparison of a Novel Rapid Chromogenic Biochemical Assay the Carba NP Test with the Modified Hodge Test for Detection of Carbapenemase-Producing Gram-Negative Bacilli

摘要

We compared carbapenemase detection among 271 Gram-negative bacilli (of which 131 were carbapenemase producers) using a novel chromogenic rapid test—the Carba NP test (CNP)—and the modified Hodge test (MHT). Sensitivities were comparable (CNP, 100%, versus MHT, 98%; P = 0.08), but CNP was more specific (100% versus 80%; P < 0.0001) and faster.