Adherence to Antiretroviral Therapy Among HIV-Positive Pregnant Womenon followup at Mizan Tepi University Teaching and Tepi General HospitalsSouthwest Ethiopia

摘要

The introduction of highly active antiretroviral therapyhas not only improved longevity in human immunodeficiency virus (HIV)–infectedindividuals but in addition has had a significant impact on the rate ofmother-to-child transmission of the infection. To assessantiretroviral therapy adherence among HIV-positive pregnant women on follow-upat antiretroviral therapy clinic of Mizan Tepi University Teaching and TepiGeneral Hospitals. A descriptive cross-sectional study wasundertaken in antiretroviral therapy clinics of Mizan Tepi University Teachingand Tepi General Hospitals from April to May 2018. Data were collected throughface to face interview using structured and pretested questionnaires andanalyzed using Statistical Package for Social Sciences version 20. Majority of the patients had good adherence to theirantiretroviral therapy, 68 (66.00%). Medication side effects, 12 (34.00%) andforgetfulness and distance of the hospital from home, each accounting 11(31.00%) were the main reasons for nonadherence among nonadherent patients.Frequency of counseling ( = .000), CD4 count (χ =37.529, = .000), World Health Organization’s clinical stage(χ = 17.515, = .000), stigma (χ =70.426, = .000), and family support (χ = 46.383, = .000) were found to be associated with patients’medication adherence. The overall patient adherence toantiretroviral therapy in the study facilities was good. Collaborative workamong patients, health care organizations, and the public are necessary totackle the adherence obstacles and enhance patient adherence to the prescribedmedication.