α-Synuclein (αSyn) Preformed Fibrils Induce Endogenous αSyn Aggregation Compromise Synaptic Activity and Enhance Synapse Loss in Cultured Excitatory Hippocampal Neurons

摘要

Author contributions: Q.W. and V.M.-Y.L. designed research; Q.W. and D.M.R. performed research; Q.W. analyzed data; Q.W. wrote the first draft of the paper; Q.W., H.T., J.Q.T., D.A.C., and V.M.-Y.L. edited the paper; V.M.-Y.L. contributed unpublished reagents/analytic tools.