PSXVII-11 Effect of supplementation with brewer yeast hydrolysate on growth performance blood profile fecal score fecal microbial and rectal temperature in weanling pigs challenged with lipopolysaccharide.

摘要

The objective of this study was to determine the effects of brewer yeast hydrolysate supplementation on growth performance, blood profile, fecal score, and fecal microbial and rectal temperature in weanling pigs challenged with lipopolysaccharide (LPS).A total of 40crossbred weanling pigs [(Yorkshire x Landrace) x Duroc] with an average body weight of 8.15 ± 0.87 kg were used in a 42-d experiment.Pigs were randomly allotted to four dietary treatments (5 pigs / replication / treatment) according to their initial body weight and sex. Treatments were as follows: TRT 1, basal diet + Saline injection; TRT2, basal diet + LPS challenge; TRT3, basal diet + 1.0% Brewer yeast hydrolysate + saline injection and TRT4, basal diet + 1.0% Brewer yeast hydrolysate + LPS challenge. The LPS was diluted in sterile saline solution and injected at 0.1 g/kg of BW at the 4th week.All data were subjected to the statistical analysis asa completely randomized design, with a 2 x 2 factorialarrangement using the GLM procedures of SAS.Pig fed diets supplemented with brewer yeast hydrolysate had significantly higher (P = 0.02) ADFI from weeks 2 to 4 as well as G:F during the whole experimental period than pigs fed diets without brewer yeast hydrolysate.Fecal E. coli counts in pigs unchallenged (4.65) with LPS tended to decrease (P = 0.08) compared with challenged (4.53). Pigs received diets supplemented with brewer yeast hydrolysate(4.69, 4.87, respectively) had the tendency of increasing on fecal E. coli and salmonella counts after LPS challenge compared with non-supplemented (4.60, 4.73, respectively) pigs (P = 0.07, 0.08, respectively).Effects Hydrolysate supplementationon on growth performance, fecal microflora, rectal temperature, and blood profiles were detected. In conclusion, the supplementation of 1.0% brewer yeast hydrolysate can improve ADFI and G:F in weanling pigs.