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Human Inhalation Exposure to Aerosol and Health Effect: Aerosol Monitoring and Modelling Regional Deposited Doses

机译:人体吸入暴露于气溶胶​​和对健康的影响:气溶胶监测和区域沉积剂量建模

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摘要

Since poor air quality affects human health in the short and long term, much research has been performed on indoor and outdoor aerosol exposure; however, there is a lack of specific data on the exposure and health risks of inhalable aerosols that contain bioaerosol in different environments of human life. To investigate the potential exposure to inhalable aerosols (in the monitoring of particulate matter (PM) based on R modeling, variations of PM depend on the ventilation system and bioaerosols based on size distribution) in various environments, the special viability and culturability of bioaerosols and their deposition doses in the respiratory system were evaluated. We conducted exposure assessments on inhalable aerosols in various indoor environments (childcare facilities, schools, commercial buildings, elderly and homes). The fractions of PM (PM , PM and PM ) were investigated and, for the bioaerosol, the viability, culturability, inhalation daily dose and the deposited dose of the aerosol in the respiratory system were calculated to evaluate the human health effects. For two years, the distribution of the indoor PM concentration was high in all PM fractions in schools and commercial buildings, and low in the elderly and at homes. For airborne bacteria, the highest concentrations were shown in the childcare facility during the four seasons, while airborne fungi showed high concentrations in the buildings during the spring and summer, which showed significant differences from other investigated environments (between the buildings and elderly and homes: < 0.05). The viability and culturability for the bioaerosol showed no significant difference in all environments, and the correlation between inhalable PM and bioaerosol obtained from the six-stage impactor showed that the coefficient of determination (R ) between coarse particles (PM , the size of stage 2–3) and cultivable airborne bacteria ranged from 0.70 (elderly and homes) to 0.84 (school) during the summer season.
机译:由于不良的空气质量短期和长期都会影响人类健康,因此已经进行了许多有关室内和室外气雾暴露的研究。但是,缺乏有关在人类不同生活环境中含有生物气溶胶的可吸入气溶胶的暴露和健康风险的具体数据。为了研究在各种环境下可吸入气雾剂的潜在暴露(在基于R模型的颗粒物(PM)监测中,PM的变化取决于通风系统和基于尺寸分布的生物气溶胶),生物气溶胶的特殊生存能力和可培养性以及评估它们在呼吸系统中的沉积剂量。我们对各种室内环境(儿童保育设施,学校,商业建筑,老人和家庭)中的可吸入气雾剂进行了暴露评估。研究了PM的比例(PM,PM和PM),并计算了生物气溶胶的生存能力,可培养性,吸入日剂量和在呼吸系统中的沉积剂量,以评估其对人类健康的影响。两年来,室内PM浓度在学校和商业建筑中所有PM组分中的分布较高,而在老年人和家庭中较低。对于空气传播的细菌来说,在四个季节中,儿童保育设施中的浓度最高,而在春季和夏季,空气中的真菌在建筑物中的浓度较高,这与其他调查环境(建筑物与老年人和家庭之间)存在显着差异: <0.05)。生物气雾剂的生存能力和可培养性在所有环境中均无显着差异,可吸入颗粒物与六级撞击器获得的生物气溶胶之间的相关性表明,粗颗粒之间的测定系数(R)(PM,第二阶段的大小) –3)和可培养的空气传播细菌在夏季的范围从0.70(老人和家庭)到0.84(学校)。

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