Langerhans Histiocytosis Renders a Differential and Complementary Diagnosis for a Sjögren Syndrome Female Presenting with a Hypophyseal Mass Pulmonary Emphysema and Thyroid Nodules

摘要

Hematoxylin and eosin staining of the thyroid nodule showed numerous Langerhans-type cells (black arrow) (400 × original magnification)(Fig. 2a), within a background of eosinophils (blue arrow) and plasma cells (yellow arrow) (hematoxylin and eosin 200 ×)(Fig. 2b). Immunohistochemical stains (immunoperoxidase 100 ×) of the thyroid nodule were strongly positive for CD1a (Fig. 2c) and S-100 (Fig. 2d)