Leukemia stem cell gene expression signatures contribute to acute myeloid leukemia risk stratification

摘要

The majority of patients with acute myeloid leukemia (AML) will die of their disease. Nevertheless, the prognosis of AML varies widely. Some AML patients may be cured by chemotherapy alone, while others require approaches such as allogeneic stem cell transplantation to have the best chance of long-term survival. As physicians, we are often asked by our AML patients: “How likely is this treatment going to work, and how long do I have to live?”