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John Mendelsohn: A visionary scientist oncologist and leader

机译:约翰·门德尔松(John Mendelsohn):一位有远见的科学家肿瘤学家和负责人

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摘要

Dr. John Mendelsohn is credited for the concept of targeting the epidermal growth factor receptor (EGFR), providing the first evidence of anticancer activity of antagonist anti-EGFR mAb, and developing the Erbitux (Cetuximab) drug for cancer patients. During his professional journey, Dr. Mendelsohn also helped to build and elevate the status of three cancer cancers, all while touching the lives of cancer patients around the globe. He was a towering figure, and his passing in January 2019 casts a very long shadow over the entire field of cancer research and treatment. Although no one person can ever adequately fill John Mendelsohn's very large shoes, we can all learn by his remarkable example. Here we discuss Dr. Mendelsohn's professional life to spotlight his influence on oncology and also share personal reflections from us and several colleagues: Tony Hunter, Robert A. Weinberg, Robert C. Bast, Raymond Sawaya, David M. Gershenson, Christopher J Logothetis, Stanley R. Hamilton, Mien-Chie Hung, and George M. Stancel. Kumar et al. Can Res 2019; 79: .
机译:John Mendelsohn博士因靶向表皮生长因子受体(EGFR)的概念而闻名,它为拮抗剂抗EGFR mAb的抗癌活性提供了第一个证据,并为癌症患者开发了Erbitux(西妥昔单抗)药物。在他的职业生涯中,孟德尔森博士还帮助建立和提高了三种癌症的地位,同时还影响了全球癌症患者的生活。他是一个高大的人物,他在2019年1月的去世给整个癌症研究和治疗领域蒙上了非常长的阴影。尽管没有人能充分填满约翰·门德尔松(John Mendelsohn)的那双大鞋子,但我们都能从他的杰出榜样中学到东西。在这里,我们讨论Mendelsohn博士的职业生涯,以凸显他对肿瘤学的影响,并分享我们和其他同事的个人看法:Tony Hunter,Robert A. Weinberg,Robert C. Bast,Raymond Sawaya,David M. Gershenson,Christopher J Logothetis,斯坦利·R·汉密尔顿(Stanley R. Kumar等。 Can Res 2019; 79 :。

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