Correction: APR-246 reactivates mutant p53 by targeting cysteines 124 and 277

摘要

mass spectra of p53 core domains. – Reaction titration with MQ or MQ-H. p53 core domains were incubated with MQ at 50–200 µM (wt and R273H) or 10–50 µM (R175H) concentration ranges. One MQ adduct increased the molecular mass of p53 core domains by 137 Da. Structure of MQ and MQ-H