Identification and validation of m6A RNA methylation regulators with clinical prognostic value in Papillary thyroid cancer

摘要

The overview of m A RNA methylation regulators in PTC. A Vioplot which visualized the differentially expressed m A regulators in PTC (blue represents normal tissues and red represents tumor tissues). The mRNA levels of 19 m A regulators in PTC. Red means this gene is up-regulated while green means this gene is down-regulated (*P c The validation of IGF2BP2 expression level by immunohistochemical staining. The result showed that the expression level of IGF2BP2 was higher in PTC tissue than normal thyroid tissue. Spearman correlation analysis of the 19 m A regulators in PTC. The “X” represents that the correlation between this pair of genes does not have statistical significance (P > 0.05). The number in every box is the Spearman correlation coefficient between two genes