BMSCs and BMSCs progenitors exhibit a unique gene expression profile. Representative pictures of BMSCs and BMSCs with mitochondrial staining using MitoTracker (red), Alizarin staining (AZR) for matrix mineralization and Oil Red O staining (ORO) showing the morphological and differentiation-induced differences between the murine cell lines. Enrichment of genes of functional GO categories from microarray. Gene expression profiling in BMSCs (white bars) and BMSCs cultured in basal conditions (black bars): genes involved in insulin signaling such as , and ; glucose transporters such as , and ; adipocytic genes such as , and ; genes involved in lipid metabolism such as , and ; autophagy genes such as , and ; bioenergetic genes such as , and ; inflammatory genes such as , and ; senescence-associated markers such as , and ; osteoblast marker genes such as , , and . Data are presented as the mean fold change (F.C.) of gene expression normalized to BMSCs expression ± SEM, ( = 3 per group); (* P P adipo vs BMSCs , two-tailed unpaired Student’s test)
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机译：BMSC和BMSC祖细胞表现出独特的基因表达谱。具有线粒体染色（使用MitoTracker（红色），用于基质矿化的茜素染色（AZR）和油红O染色（ORO））的线粒体染色的BMSC和BMSC的代表性图片显示了鼠细胞系之间的形态和分化诱导差异。从微阵列富集功能性GO类别的基因。 BMSC（白条）和在基础条件下培养的BMSC（黑条）中的基因表达谱：涉及胰岛素信号的基因，例如和；葡萄糖转运体，如和;脂肪细胞基因，如和;参与脂质代谢的基因，如和;自噬基因，如和;生物能量基因，如和;炎性基因，如和;衰老相关标记，例如和；成骨细胞标记基因，如和。数据表示为相对于BMSCs表达的标准基因表达的平均倍数变化（F.C.）±±SEM，（每组= 3）； （* P P adipo与BMSC，两尾未配对学生测试）
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