Functional versus functional and anatomical criteria-guided ranibizumab treatment in patients with neovascular age-related macular degeneration – results from the randomized phase IIIb OCTAVE study

摘要

Patient disposition. The reasons for screening failure were: patients did not meet the diagnostic or severity criteria. (44 patients [41.5%]), unacceptable test procedure results (20 patients [18.9%]), other (20 patients [18.9%]), and patients’ withdrawal of consent (19 patients [17.9%]). *The study was prematurely terminated due to the emergence of OCT as an important technique for diagnosis and making treatment/retreatment decisions in nAMD; none of the patients completed 24 months. nAMD, neovascular age-related macular degeneration; OCT, optical coherence tomography; VA, visual acuity