MicroRNA-107 is a novel tumor suppressor targeting POU3F2 in melanoma

摘要

miR-107 is under-expressed in human melanoma cell lines and tumors. The comparison of miRNA-107 expression in melanoma cancer lines (SK-MEL-1, A375, G-361, SK-MEL-3, SH-4, and SK-MEL-24) and primary melanocytes (PM-1, PM-2) from healthy donors. The comparison of miRNA-107 expression in nevi, primary and metastatic melanoma human samples. The miRNA was quantified by realtime PCR. The data were presented as mean ± SD of at least three independent experiments (**p #p