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Small Centers with Big Ventures: Autologous Stem Cell Transplantation Survival Data

机译:有大型企业的小型中心:自体干细胞移植存活数据

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摘要

We present the first-ever autologous stem cell transplantation (ASCT) outcome data from a secondary-care healthcare facility. Albeit exact details of patient and disease characteristics and co-morbidity scores for all patients are not available, the engraftment and survival data is very similar to those published from large tertiary-care cancer centres, both regionally and internationally. Transplant Related Mortality (TRM) of 3.1% is within the expected range and includes a patient who died of acute drug reaction (ADR) during conditioning chemotherapy, prior to the ASCT. Furthermore, cyclophosphamide mobilization chemotherapy is given in the outpatient setting. This study is important in terms of healthcare resource optimization as well as patients’ convenience and highlights that ASCT can be performed in a safe and effective manner with comparable survival rates even at a DGH, provided the centre stays abreast with the recent developments and can offer its patients with standard of care treatment of the era.
机译:我们提供了来自二级保健医疗机构的首个自体干细胞移植(ASCT)结果数据。尽管无法获得所有患者的病情和疾病特征以及合并症分数的确切详细信息,但其植入和生存数据与区域和国际大型三级癌症中心的数据非常相似。 3.1%的移植相关死亡率(TRM)在预期范围内,包括在ASCT之前因调理化疗而死于急性药物反应(ADR)的患者。此外,在门诊患者中进行环磷酰胺动员化疗。这项研究对于医疗资源的优化以及患者的便利性而言非常重要,并且强调指出,即使该中心与DGH保持同步,ASCT仍可以安全有效地以相当的存活率进行,并且其患者具有标准护理时代的治疗方法。

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