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Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging

机译：将空间分辨的三维MALDI IMS与体内磁共振成像相集成

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摘要

We have developed a method for integrating three dimensional—volume reconstructions of spatially resolved matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) ion images of whole mouse heads with high-resolution images from other modalities in an animal-specific manner. This approach enabled us to analyze proteomic profiles from MALDI IMS data with corresponding in vivo data provided by magnetic resonance imaging.

机译：我们已经开发出一种方法，用于以动物特定的方式将整个鼠标头的空间分辨矩阵辅助激光解吸/电离成像质谱（MALDI IMS）离子图像的三维重建与其他模式的高分辨率图像相集成。这种方法使我们能够分析MALDI IMS数据中的蛋白质组学概况以及磁共振成像提供的相应体内数据。

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期刊名称 other
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Tuhin K Sinha; Sheerin Khatib-Shahidi; Thomas E Yankeelov; Khubaib Mapara; Moneeb Ehtesham; D Shannon Cornett; Benoit M Dawant; Richard M Caprioli; John C Gore;
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年(卷),期 -1(5),1
年度 -1
页码 57–59
总页数 7
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专利

1. Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging [J] . Sinha TK, Khatib-Shahidi S, Yankeelov TE, Nature methods . 2008 ,第1期

机译：将空间分辨的三维MALDI IMS与体内磁共振成像相集成
2. Spatially Resolved Quantification of Gadolinium(III)-Based Magnetic Resonance Agents in Tissue by MALDI Imaging Mass Spectrometry after In Vivo MRI [J] . Aichler Michaela, Huber Katharina, Schilling Franz, Angewandte Chemie . 2015 ,第14期

机译：体内MRI后MALDI成像质谱法对组织中基于（（III）的磁共振剂进行空间分辨定量
3. Scar voltage threshold determination using ex vivo magnetic resonance imaging integration in a porcine infarct model: Influence of interelectrode distances and three-dimensional spatial effects of scar [J] . Tung Roderick, Kim Steve, Yagishita Daigo, Heart rhythm: the official journal of the Heart Rhythm Society . 2016 ,第10期

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4. A Met a-Classifier for Detecting Prostate Cancer by Quantitative Integration of In Vivo Magnetic Resonance Spectroscopy and Magnetic Resonance Imaging [C] . Satish Viswanath, Pallavi Tiwari, Mark Rosen, Conference on Medical Imaging 2008: Computer-Aided Diagnosis; 20080219-21; San Diego,CA(US) . 2008

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5. Interactions between spin transport and dynamics studied using spatially resolved imaging and magnetic resonance. [D] . Page, Michael Roy. 2016

机译：使用空间分辨成像和磁共振研究了自旋输运与动力学之间的相互作用。
6. Use of three-dimensional time-resolved phase-contrast magnetic resonance imaging with vastly undersampled isotropic projection reconstruction to assess renal blood flow in a renal cell carcinoma patient treated with sunitinib: a case report [O] . Tatsuya Takayama, Yasuo Takehara, Masataka Sugiyama, 2014

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7. Integrating spatially resolved three-dimensional maldi ims with in vivo magnetic resonance imaging [O] . Tuhin K Sinha, Sheerin Khatib-shahidi, Thomas E Yankeelov, 2015

机译：将空间分辨的三维maldi ims与体内磁共振成像相结合
8. Magnetic Resonance Spectroscopy Imaging and Function Magnetic Resonance Imaging of Neurofibromatosis Type I: In vivo Pathophysiology, Brain-Behavior Relationships and Reading Disabilities [R] . Cutting, L. E. 2005

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Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging

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