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PACLITAXEL POLIGLUMEX AND CARBOPLATIN AS FIRST-LINE THERAPY IN OVARIAN PERITONEAL OR FALLOPIAN TUBE CANCER: A PHASE I AND FEASIBILITY TRIAL OF THE GYNECOLOGIC ONCOLOGY GROUP

机译：卵巢癌腹膜或淋巴管癌的一线治疗药物：帕加西妥POLIGLUMEX和卡铂：妇科肿瘤学组的第一阶段和可行性试验

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PurposeTo estimate the maximum tolerated dose (MTD) of paclitaxel poliglumex (PPX) in combination with carboplatin in patients with chemotherapy-naive ovarian, primary peritoneal or fallopian tube cancer, and to assess the feasibility of administering multiple cycles of this regimen.

机译：目的评估未接受化疗的卵巢癌，原发性腹膜癌或输卵管癌患者中紫杉醇poliglumex（PPX）联合卡铂的最大耐受剂量（MTD），并评估该方案多周期给药的可行性。

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期刊名称 other
作者
Mark A. Morgan; Kathleen M. Darcy; Peter G. Rose; Koen DeGeest; Michael A. Bookman; James K. Aikins; Michael W. Sill; Robert S. Mannel; Cecilia Allievi; Merrill J. Egorin;
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年(卷),期 -1(110),3
年度 -1
页码 329–335
总页数 15
原文格式 PDF
正文语种
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关键词
phase I trial paclitaxel poliglumex ovarian cancer chemotherapy carboplatin;

机译：一期试验;紫杉醇;卵巢癌;化学疗法;卡铂;

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专利

1. Paclitaxel poliglumex and carboplatin as first-line therapy in ovarian, peritoneal or fallopian tube cancer: a phase I and feasibility trial of the Gynecologic Oncology Group. [J] . Morgan MA, Darcy KM, Rose PG, Gynecologic Oncology: An International Journal . 2008,第3期

机译：紫杉醇poliglumex和卡铂作为卵巢癌，腹膜癌或输卵管癌的一线治疗药物：妇科肿瘤学小组的第一阶段和可行性试验。
2. A phase i study with an expanded cohort to assess the feasibility of intravenous paclitaxel, intraperitoneal carboplatin and intraperitoneal paclitaxel in patients with untreated ovarian, fallopian tube or primary peritoneal carcinoma: A Gynecologic Oncology Group study [J] . GouldN., SillM.W., MannelR.S., Gynecologic Oncology: An International Journal . 2012,第1期

机译：一项扩大的队列研究的第一阶段，以评估未经治疗的卵巢癌，输卵管癌或原发性腹膜癌患者中静脉使用紫杉醇，腹膜内卡铂和腹膜内紫杉醇的可行性：妇科肿瘤小组研究
3. A phase i study with an expanded cohort to assess feasibility of intravenous docetaxel, intraperitoneal carboplatin and intraperitoneal paclitaxel in patients with previously untreated ovarian, fallopian tube or primary peritoneal carcinoma: A Gynecologic Oncology Group study [J] . GouldN., SillM.W., MannelR.S., Gynecologic Oncology: An International Journal . 2012,第3期

机译：一项扩大队列研究的第一阶段研究，用于评估先前未接受治疗的卵巢癌，输卵管癌或原发性腹膜癌患者中静脉使用多西紫杉醇，腹膜内卡铂和腹膜内紫杉醇的可行性：妇科肿瘤学小组研究
4. Prophylaxis and Treatment of Advanced Gastric Cancer with Peritoneal Metastasis with Intraperitoneal(I.P.) Administration of Liposome-Carboplatin(Lipo-CBDCA) and Its Clinical Trial in Peritoneal Carcinomatosis(P.C.). [C] . Mizuno I., Yotsuyanagi T., Ishida M., International Gastric Cancer Congress . 2011

机译：腹膜内（I.P，I.P）对腹膜转移的预防和治疗晚期胃癌（I.P。）脂质体 - 卡铂（Lipo-CBDCA）的施用及其在腹膜癌症中的临床试验（P.C。）。
5. Analysis of Oncologic Outcomes Associated with Anti-adhesion Sodium Hyaluronate-Carboxymethylcellulose Barrier Following Optimal or Complete Cytoreductive Surgery for Ovarian, Fallopian Tube, and Peritoneal Cancers. [D] . Krill, Lauren. 2014

机译：卵巢癌，输卵管癌和腹膜癌的最佳或完全细胞还原手术后，与抗粘连透明质酸钠-羧甲基纤维素屏障相关的肿瘤学结果分析。
6. A phase I study with an expanded cohort to assess the feasibility of intravenous paclitaxel intraperitoneal carboplatin and intraperitoneal paclitaxel in patients with untreated ovarian fallopian tube or primary peritoneal carcinoma: A Gynecologic Oncology Group study [O] . Natalie Gould, Michael W. Sill, Robert S. Mannel, -1

机译：Ⅰ期关于扩展队列的阶段研究以评估静脉内紫杉醇腹膜内卡铂和腹膜内紫杉醇在未处理卵巢输卵管或原发性腹膜癌患者中的可行性：妇科肿瘤学群体研究
7. A phase I study with an expanded cohort to assess the feasibility of intravenous paclitaxel, intraperitoneal carboplatin and intraperitoneal paclitaxel in patients with untreated ovarian, fallopian tube or primary peritoneal carcinoma: A Gynecologic Oncology Group study [O] . Natalie Gould, Michael W. Sill, Robert S. Mannel, 2012

机译：Ⅰ期关于扩展队列的阶段研究，以评估静脉内紫杉醇，腹膜内卡铂和腹膜内紫杉醇在未处理卵巢，输卵管或原发性腹膜癌患者中的可行性：妇科肿瘤学群体研究

PACLITAXEL POLIGLUMEX AND CARBOPLATIN AS FIRST-LINE THERAPY IN OVARIAN PERITONEAL OR FALLOPIAN TUBE CANCER: A PHASE I AND FEASIBILITY TRIAL OF THE GYNECOLOGIC ONCOLOGY GROUP

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