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Differential effects of chronic antidepressant treatment on shuttle box escape deficits induced by uncontrollable stress

机译：慢性抗抑郁药对无法控制的压力导致梭箱逃逸缺陷的差异作用

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摘要

RationaleThe transient behavioral deficit produced in rodents by typical learned helplessness (LH) procedures limits the utility of LH in identifying the therapeutic mechanisms associated with chronic antidepressant administration. In addition, LH procedures do not differentiate between different antidepressant classes as observed in the forced swim test.

机译：基本原理通过典型的习得性无助（LH）程序在啮齿动物中产生的短暂行为缺陷限制了LH在确定与慢性抗抑郁药相关的治疗机制中的效用。此外，在强迫游泳试验中，LH程序不能区分不同的抗抑郁药。

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期刊名称 other
作者
Gerald Valentine; Antonia Dow; Mounira Banasr; Brian Pittman; Ronald Duman;
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年(卷),期 -1(200),4
年度 -1
页码 585–596
总页数 21
原文格式 PDF
正文语种
中图分类
关键词
Depression Animal model Uncontrollable stress Inescapable shock Learned helplessness Shuttle box SSRI Desipramine Contextual fear;

机译：抑郁症;动物模型;不可控制的压力;不可避免的休克;习得性的无助;梭箱;SSRI;Desipramine;情境恐惧;

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专利

1. Differential effects of chronic antidepressant treatment on shuttle box escape deficits induced by uncontrollable stress. [J] . Valentine G, Dow A, Banasr M, Psychopharmacology . 2008,第4期

机译：慢性抗抑郁治疗对不受控制的压力引起的穿梭箱逃逸缺陷的不同作用。
2. Differential effects of chronic antidepressant treatment on shuttle box escape deficits induced by uncontrollable stress [J] . Gerald Valentine, Antonia Dow, Mounira Banasr, Psychopharmacology . 2008,第4期

机译：慢性抗抑郁药对无法控制的压力导致梭箱逃逸缺陷的差异作用
3. Long-lasting behavioral effects and recognition memory deficit induced by chronic mild stress in mice: effect of antidepressant treatment. [J] . Elizalde N, Gil-Bea FJ, Ramirez MJ, Psychopharmacology . 2008,第1期

机译：慢性轻度应激在小鼠中引起的长期行为影响和识别记忆障碍：抗抑郁药治疗的作用。
4. Antidepressant-like activity of agomelatine in the mouse unpredictable chronic mild stressed model [C] . Mutlu O., Ulak G., Gumuslu E., European Congress of Pharmacology . 2012

机译：在小鼠不可预测的慢性轻度胁迫模型中抗抑郁的致癌物活性
5. The effects of chronic naltrexone treatment on lateral hypothalamic self-stimulation, stimulation-escape, and stimulation-induced feeding [D] . Uysal, Suzan. 1990

机译：慢性纳曲酮治疗对下丘脑外侧自我刺激，刺激逃避和刺激诱发的进食的影响
6. Differential Effects of Chronic Antidepressant Treatment on Swim Stress- and Fluoxetine-Induced Secretion of Corticosterone and Progesterone [O] . GARY E. DUNCAN, DARIN J. KNAPP, STANLEY W. CARSON, -1

机译：慢性抗抑郁药对游泳应激和氟西汀诱导的皮质酮和孕酮分泌的不同作用
7. Differential effects of chronic antidepressant treatment on shuttle box escape deficits induced by uncontrollable stress [O] . Gerald Valentine, Antonia Dow, Mounira Banasr, 2008

机译：慢性抗抑郁治疗对无法控制应力诱导的梭箱逃生缺陷的差异影响
8. Differential Effects of Controllable and Uncontrollable Stress on Immune Function in Humans. [R] . Weisse, C. S. 1989

机译：可控和不可控应激对人体免疫功能的不同影响。

Differential effects of chronic antidepressant treatment on shuttle box escape deficits induced by uncontrollable stress

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