Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients

摘要

BackgroundTwo nucleoside-reverse-transcriptase-inhibitors (NRTIs)-abacavir and didanosine-may each be associated with excess risk of myocardial infarction (MI). The reproducibility of this finding in an independent data set was explored and plausible biological mechanisms were sought.