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Formulation and In Vitro-In Vivo Evaluation of Black Raspberry Extract-Loaded PLGA/PLA Injectable Millicylindrical Implants for Sustained Delivery of Chemopreventive Anthocyanins

机译：制剂和体外体内评价黑覆盆子提取物的PLGA / PLA可注射杀菌植入物用于持续递送化学预防性花青素

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摘要

PurposeThe objective of this study was to formulate and evaluate freeze-dried black raspberry (FBR) ethanol extract (RE) loaded poly(DL-lactic-co-glycolic acid) (PLGA) and poly(DL-lactic acid) (PLA) injectable millicylindrical implants for sustained delivery of chemopreventive FBR anthocyanins (cyanidin-3-sambubioside (CS), cyanidin-3-glucoside (CG) and cyanidin-3-rutinoside (CR)).

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作者
Kashappa Goud H. Desai; Karl F. Olsen; Susan R. Mallery; Gary D. Stoner; Steven P. Schwendeman;
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年(卷),期 -1(27),4
年度 -1
页码 628–643
总页数 32
原文格式 PDF
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关键词
black raspberry anthocyanins chemoprevention controlled release inclusion complex injectable millicylindrical implants microencapsulation oral cancer PLA PLGA Triacetyl-β-cyclodextrin;

机译：黑莓花色苷;化学预防;控释;包合复合物;可注射的米粉工业植入物;微囊化;口腔癌;PLA;PLGA;三乙酰-β-环糊精;

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1. Formulation and In Vitro-In Vivo Evaluation of Black Raspberry Extract-Loaded PLGA/PLA Injectable Millicylindrical Implants for Sustained Delivery of Chemopreventive Anthocyanins [J] . Kashappa Goud H. Desai, Karl F. Olsen, Susan R. Mallery, Pharmaceutical Research . 2010,第4期

机译：黑色树莓提取物负载的PLGA / PLA可注射的Millicylindical植入物的配方和体外评估，用于化学预防性花青素的持续递送。
2. Formulation and in vitro-in vivo evaluation of black raspberry extract-loaded PLGA/PLA injectable millicylindrical implants for sustained delivery of chemopreventive anthocyanins. [J] . Desai KG, Olsen KF, Mallery SR, Pharmaceutical research . 2010,第4期

机译：黑色树莓提取物负载PLGA / PLA可注射的Millicylindrical植入物的配方和体外体内评估，用于化学预防性花色苷的持续递送。
3. Polymeric and Non Polymeric Injectable In-situ Forming Implant Systems for Sustained Delivery of Lornoxicam: In vitro and In vivo Evaluation [J] . Soad A. Yehia, Sally A.A. Halim, Mary Y. Aziz Current drug delivery . 2018,第8期

机译：聚合物和非聚合物可注射的原位形成植入系统，用于血岭喹啉的持续递送：体外和体内评价
4. Development of a Novel Release Phantom for Improved In Vitro-In Vivo Correlation of Drug Release From In Situ Forming Polymer Implants [C] . Christopher Hernandez, Luis Solorio, Haoyan Zhou, Society for Biomaterials annual meeting and exposition . 2014

机译：新型释放幻影的开发，用于改进药物从原位形成聚合物植入物中的体内离体相关性
5. 1. Evaluation of polycarbophil coated liposomes and membrane permeation of free and liposomal drugs, 2. In vitro-in vivo evaluation of nicardipine HCl sustained-release formulations [D] . Sorasuchart, Waranush. 1998

机译：1.评估聚卡波非包衣的脂质体和游离药物和脂质体药物的膜渗透性，2.尼卡地平HCl缓释制剂的体外-体内评估
6. Evaluation of Polyphenol Anthocyanin-Enriched Extracts of Blackberry Black Raspberry Blueberry Cranberry Red Raspberry and Strawberry for Free Radical Scavenging Reactive Carbonyl Species Trapping Anti-Glycation Anti-β-Amyloid Aggregation and Microglial Neuroprotective Effects [O] . Hang Ma, Shelby L. Johnson, Weixi Liu, 2018

机译：黑莓黑莓蓝莓蔓越莓红莓和草莓中富含多酚花青素的提取物对自由基清除活性羰基类诱捕抗糖基化抗β-淀粉样蛋白聚集和小胶质神经保护作用的评价
7. Characterization and evaluation of β-glucan formulations as injectable implants for protein and peptide delivery. [O] . Jacobs, Simone, Bunt, Craig R, Wu, Zimei, 2012

机译：β-葡聚糖制剂作为蛋白质和肽递送的可注射植入物的特性和评估。

Formulation and In Vitro-In Vivo Evaluation of Black Raspberry Extract-Loaded PLGA/PLA Injectable Millicylindrical Implants for Sustained Delivery of Chemopreventive Anthocyanins

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