THREE-DIMENSIONAL ANALYSIS OF TUMOUR VASCULAR CORROSION CASTS USING STEREOIMAGING AND MICRO-COMPUTED TOMOGRAPHY

摘要

ObjectiveIn order to perform effective translational research for cancer therapy, we need to employ pre-clinical models which reflect the clinical situation. The purpose of this study was to quantitatively compare the vascular architecture of human colorectal cancer and experimental tumour models to determine the suitability of animal models for vascular studies and antivascular therapy.