MRI-based Extended Ordered Values More Efficiently Differentiate Cartilage Loss in Knees With and Without Joint Space Narrowing than Region-specific approaches using MRI or Radiography – Data from the OA Initiative

摘要

ObjectiveThe sensitivity to change of quantitative analysis of cartilage in knee osteoarthritis using MRI is compromised by the spatial heterogeneity of cartilage loss. We explore whether extended (medial-lateral) “ordered values” (OV) are superior to conventional approaches of analyzing subregional cartilage thickness loss and to radiography, in differentiating rates of progression in knees with and without joint space narrowing (JSN).