Photodynamic effects of methylene blue-loaded polymeric nanoparticles on dental plaque bacteria

摘要

Background and ObjectivesPhotodynamic therapy (PDT) is increasingly being explored for treatment of oral infections. Here, we investigate the effect of PDT on human dental plaque bacteria in vitro using methylene blue (MB)-loaded poly(lactic-co-glycolic) (PLGA) nanoparticles with a positive or negative charge and red light at 665 nm.