Bicyclic C21 Terpenoids from the Marine Sponge Clathria compressa

摘要

Three new bicyclic C21 terpenoids, clathric acid (>1) and two N-acyl taurine derivatives, clathrimides A (>2) and B (>3) were isolated from the marine sponge Clathria compressa. The structures of these compounds were elucidated by interpretation of spectroscopic data. Clathric acid showed mild antibacterial activity against several Gram-positive bacteria.