ILF-3 is a regulator of the neural plate border marker Zic1 in chick embryos

摘要

BackgroundThe neural crest is a multipotent cell type unique to the vertebrate lineage and capable of differentiating into a large number of varied cell types, including ganglia of the peripheral nervous system, cartilage and glia. An early step in neural crest specification occurs at the neural plate border, a region defined by the overlap of transcription factors of the Zic, Msx and Pax families.