首页> 美国卫生研究院文献>other >Genome-Wide Screening Reveals an EMT Molecular Network Mediated by Sonic Hedgehog-Gli1 Signaling in Pancreatic Cancer Cells

【2h】

Genome-Wide Screening Reveals an EMT Molecular Network Mediated by Sonic Hedgehog-Gli1 Signaling in Pancreatic Cancer Cells

机译：全基因组筛选揭示一个EmT分子网络介导的通过音猬因子信令中Gli1在胰腺癌细胞中

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

AimsThe role of sonic hedgehog (SHH) in epithelial mesenchymal transition (EMT) of pancreatic cancer (PC) is known, however, its mechanism is unclear. Because SHH promotes tumor development predominantly through Gli1, we sought to understand its mechanism by identifying Gli1 targets in pancreatic cancer cells.

机译：目的声刺猬（SHH）在胰腺癌（PC）的上皮间质转化（EMT）中的作用是已知的，但其机制尚不清楚。因为SHH主要通过Gli1促进肿瘤发展，所以我们试图通过鉴定胰腺癌细胞中的Gli1靶标来了解其机制。

著录项

期刊名称 other
作者
Xuanfu Xu; Yingqun Zhou; Chuangao Xie; Shu-mei Wei; Huizhong Gan; Shengli He; Fan Wang; Ling Xu; Jie Lu; Weiqi Dai; Lei He; Ping Chen; Xingpeng Wang; Chuanyong Guo;
展开▼
作者单位

展开▼
年(卷),期 -1(7),8
年度 -1
页码 e43119
总页数 16
原文格式 PDF
正文语种
中图分类
关键词

相似文献

外文文献
中文文献
专利

1. Sonic hedgehog-Gli1 signals promote epithelial-mesenchymal transition in ovarian cancer by mediating PI3K/AKT pathway [J] . Zhang Ke, Sun Caiping, Zhang Qing, Medical oncology . 2015,第1期

机译：声波刺猬-Gli1信号通过介导PI3K / AKT途径促进卵巢癌上皮-间质转化
2. CXCL12/CXCR4 Protein Signaling Axis Induces Sonic Hedgehog Expression in Pancreatic Cancer Cells via Extracellular Regulated Kinase- and Akt Kinase-mediated Activation of Nuclear Factor κB [J] . Ajay P. Singh, Sumit Arora, Arun Bhardwaj, The Journal of biological chemistry . 2012,第46期

机译：CXCL12 / CXCR4蛋白信号轴通过细胞外调节激酶和Akt激酶介导的核因子κB活化诱导胰腺癌细胞中的声波刺猬表达
3. Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling. [J] . Sanchez P, Hernandez AM, Stecca B, Proceedings of the National Academy of Sciences of the United States of America . 2004,第34期

机译：通过干扰SONIC HEDGEHOG-GLI1信号传导抑制前列腺癌的增殖。
4. E-Selectin-Mediated Rolling and Firm Adhesion of Pancreatic Cancer Cells in Shear Flow [C] . Daniel J Shea, Yi Wai Li, Konstantinos Konstantopoulos AIChE Annual Meeting . 2016

机译：E-Selectin介导的剪切流动胰腺癌细胞的轧制和坚固粘附
5. APE1/Ref-1 Redox Signaling Regulates HIF1a-Mediated CA9 Expression in Hypoxic Pancreatic Cancer Cells: Combination Treatment in Patient-Derived Pancreatic Tumor Models [D] . Logsdon, Derek Paul. 2018

机译：APE1 / Ref-1氧化还原信号调节低氧胰腺癌细胞中HIF1a介导的CA9表达：患者源性胰腺肿瘤模型的联合治疗
6. Sonic Hedgehog-Gli1 Signaling Pathway Regulates the Epithelial Mesenchymal Transition (EMT) by Mediating a New Target Gene S100A4 in Pancreatic Cancer Cells [O] . Xuanfu Xu, Bin Su, Chuangao Xie, -1

机译：声波刺猬Gli1信号通路通过介导胰腺癌细胞中的新靶基因S100A4调节上皮间质转化（EMT）。
7. Genome-wide screening reveals an EMT molecular network mediated by Sonic hedgehog-Gli1 signaling in pancreatic cancer cells. [O] . Xuanfu Xu, Yingqun Zhou, Chuangao Xie, 2012

机译：全基因组筛选揭示了由胰腺癌细胞中的sonic hedgehog-Gli1信号传导介导的EmT分子网络。

Genome-Wide Screening Reveals an EMT Molecular Network Mediated by Sonic Hedgehog-Gli1 Signaling in Pancreatic Cancer Cells

摘要

著录项

相似文献

相关主题

期刊订阅