Stress increases voluntary alcohol intake but does not alter established drinking habits in a rat model of post-traumatic stress disorder

摘要

BackgroundLife altering anxiety disorders, such as post-traumatic stress disorder (PTSD), can co-occur at high rates with substance use disorders. Alcoholism, compared to other substance use disorders, is particularly common. Rodent studies of acute stress effects on alcohol consumption show stress can alter ethanol (EtOH) consumption. This study examined voluntary EtOH consumption in male Long-Evans rats that had undergone a stress-enhanced fear learning (SEFL) procedure.