Report from the 16th International Histocompatibility and Immunogenetics Workshop (IHIW) Component: Population Global Distribution of Killer Immunoglobulin-like Receptor (KIR) and Ligands

摘要

In the last fifteen years published reports have described KIR gene-content frequency distributions in more than 120 populations worldwide. However, there have been limited studies examining these data in aggregate in order to detect overall patterns of variation at regional and global levels. Here, we present a summary of the collection of KIR gene-content data for 105 worldwide populations collected as part of the 15^th and 16^th International Histocompatibility and Immunogenetics Workshops, and preliminary results for data analysis.The data were contributed by thirty-four laboratories during the four-year course of this project, including data for the HGDP-CEPH populations. Additionally, data from the 15^th IHIW and data contributed to the allelefrequencies.net (AFND) database were combined with the current workshop dataset