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Speckle-scale focusing in the diffusive regime with time-reversal of variance-encoded light (TROVE)

机译:散斑规模在扩散机制聚焦方差编码光(宝库)的时间反转

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摘要

Focusing of light in the diffusive regime inside scattering media has long been considered impossible. Recently, this limitation has been overcome with time reversal of ultrasound-encoded light (TRUE), but the resolution of this approach is fundamentally limited by the large number of optical modes within the ultrasound focus. Here, we introduce a new approach, time reversal of variance-encoded light (TROVE), which demixes these spatial modes by variance-encoding to break the resolution barrier imposed by the ultrasound. By encoding individual spatial modes inside the scattering sample with unique variances, we effectively uncouple the system resolution from the size of the ultrasound focus. This enables us to demonstrate optical focusing and imaging with diffuse light at unprecedented, speckle-scale lateral resolution of ~ 5 μm.
机译:长期以来,人们一直认为不可能将光聚焦在散射介质内部的扩散区域中。近来,通过超声编码光的时间反转(TRUE)已克服了此限制,但是此方法的分辨率从根本上受到超声焦点内大量光学模式的限制。在这里,我们介绍了一种新方法,即方差编码光(TROVE)的时间反转,该方法通过方差编码将这些空间模式混合,以打破超声施加的分辨率障碍。通过以独特的方差编码散射样本内部的各个空间模式,我们可以有效地将系统分辨率与超声焦点的大小分开。这使我们能够以约5μm的前所未有的散斑级横向分辨率演示扩散光的光学聚焦和成像。

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