Reliability Asymmetry and Age Influence on Dynamic Cerebral Autoregulation Measured by Spontaneous Fluctuations of Blood Pressure and Cerebral Blood Flow Velocities in Healthy Individuals

摘要

BackgroundCerebral autoregulation (CA) enables the brain to maintain stable cerebral blood flow (CBF). CA can be assessed non-invasively by determining correlations between cerebral blood flow velocity (CBFV) and spontaneous changes in blood pressure. Post-recording signal analysis methods have included both frequency- and time-domain methods. However, the test-retest reliability, cross-validation, and determination of normal values have not been adequately established.