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An on-chip multichannel droplet sorter using standing surface acoustic waves (SSAW)

机译:使用驻波表面声波(SSAW)的片上多通道液滴分选仪

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摘要

The emerging field of droplet microfluidics requires effective on-chip handling and sorting of droplets. In this work, we demonstrate a microfluidic device that is capable of sorting picoliter water-in-oil droplets into multiple outputs using standing surface acoustic waves (SSAW). This device integrates a single-layer microfluidic channel with interdigital transducers (IDTs) to achieve on-chip droplet generation and sorting. Within the SSAW field, water-in-oil droplets experience an acoustic radiation force and are pushed towards the acoustic pressure node. As a result, by tuning the frequency of the SSAW excitation, the position of the pressure nodes can be changed and droplets can be sorted to different outlets at rates up to 222 droplets s−1. With its advantages in simplicity, controllability, versatility, non-invasiveness, and capability to be integrated with other on-chip components such as droplet manipulation and optical detection units, the technique presented here could be valuable for the development of droplet-based micro total analysis systems (μTAS).
机译:液滴微流控技术的新兴领域要求对液滴进行有效的芯片上处理和分类。在这项工作中,我们演示了一种微流控设备,该设备能够使用立式声表面波(SSAW)将微微升油包水液滴分类为多个输出。该设备将单层微流体通道与叉指换能器(IDT)集成在一起,以实现芯片上液滴的产生和分类。在SSAW场内,油包水液滴会受到声辐射力,并被推向声压节点。结果,通过调整SSAW激励的频率,可以改变压力节点的位置,并且可以以高达222个液滴s -1 的速率将液滴分类到不同的出口。凭借其简单性,可控性,多功能性,非侵入性以及与其他芯片上组件(如液滴操作和光学检测单元)集成的优势,此处介绍的技术对于基于液滴的微量总量的开发可能是有价值的分析系统(μTAS)。

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