Development of a job-exposure matrix for exposure to total and fine particulate matter in the aluminum industry

摘要

Increasing evidence indicates that exposure to particulate matter (PM) at environmental concentrations increases the risk of cardiovascular disease, particularly PM with an aerodynamic diameter of less than 2.5μm (PM2.5). Despite this, the health impacts of higher occupational exposures to PM2.5 have rarely been evaluated. In part, this research gap derives from the absence of information on PM2.5 exposures in the workplace. To address this gap, we have developed a job-exposure matrix (JEM) to estimate exposure to two size fractions of PM in the aluminum industry. Measurements of total PM (TPM) and PM2.5 were used to develop exposure metrics for an epidemiologic study.TPM exposures for distinct exposure groups (DEGs) in the JEM were calculated using 8,385 personal TPM samples collected at 11 facilities (1980-2011). For 8 of these facilities, simultaneous PM2.5 and TPM personal monitoring was conducted from 2010-2011 to determine the percent of TPM that is composed of PM2.5 (%PM2.5) in each DEG. The mean TPM from the JEM was then multiplied by %PM2.5 to calculate PM2.5 exposure concentrations in each DEG.Exposures in the smelters were substantially higher than in fabrication units; mean TPM concentrations in smelters and fabrication facilities were 3.86 mg/m³ and 0.76 mg/m³, and the corresponding mean PM2.5 concentrations were 2.03 mg/m³ and 0.40 mg/m³. Observed occupational exposures in this study generally exceeded environmental PM2.5 concentrations by an order of magnitude.