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Esophageal Radioprotection by Swallowed JP4-039/F15 in Thoracic-irradiated Mice with Transgenic Lung Tumors

机译：吞咽的JP4-039 / F15在转基因肺肿瘤胸腔照射的小鼠中对食管的放射防护。

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摘要

Background/Aim:To determine whether Gramicidin S (GS)-nitroxide, JP4–039, esophageal radiation protection protected lung tumors in a transgenic model, LoxP-Stoop-LoxP Kristen Rat Sarcoma Viral oncogene (LSL-K-RAS) mice were administered intra-tracheal-Carbapenem-resistant Enterobacteriaceae (CRE) recombinase, bilateral lung tumors were confirmed at 11 weeks, then thoracic irradiation was delivered.

机译：背景/目的：为了确定转基因模型中是否有格拉西汀S（GS）-硝基氧（JP4-039），食道辐射防护保护了肺肿瘤，LoxP-Stoop-LoxP克里斯汀大鼠肉瘤病毒癌基因（LSL-K-RAS）小鼠被给予气管内对碳青霉烯耐药的肠杆菌科（CRE）重组酶，在11周时确认了双侧肺部肿瘤，然后进行了胸腔照射。

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期刊名称 other
作者
MICHAEL W. EPPERLY; JULIE P. GOFF; DARCY FRANICOLA; HONG WANG; PETER WIPF; SONG LI; JOEL S. GREENBERGER;
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作者单位

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年(卷),期 -1(28),4
年度 -1
页码 435–440
总页数 12
原文格式 PDF
正文语种
中图分类
关键词
GS-Nitroxide esophageal radioprotection transgenic lung cancer;

机译：GS-一氧化氮;食道放射防护;转基因肺癌;

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专利

1. Esophageal radioprotection by swallowed JP4-039/F15 in thoracic-irradiated mice with transgenic lung tumors. [J] . Michael W Epperly, Julie P Goff, Darcy Franicola, In vivo. . 2014 ,第4期

机译：吞咽的JP4-039 / F15在转基因肺部肿瘤的胸腔照射小鼠中对食管的放射防护。
2. Esophageal Radioprotection by Swallowed JP4-039/F15 in Thoracic-irradiated Mice with Transgenic Lung Tumors [J] . MICHAEL W. EPPERLY, JULIE P. GOFF, DARCY FRANICOLA, In vivo. . 2014 ,第4期

机译：吞咽JP4-039 / F15对转基因肺肿瘤胸腔照射的小鼠的食道放射防护。
3. Amelioration of Radiation Induced Oral Cavity Mucositis and Bone Marrow Suppression in FANCA-/- and FANCG -/- Mice Using JP4-039 in F15 Oral Liposomes [J] . Willis J., Epperly M., Fisher R., International Journal of Radiation Oncology, Biology, Physics . 2017 ,第2Suppla期

机译：辐射诱导口腔腔粘膜肌炎和FANGA - / - 和FANCG - / - 骨髓抑制在F1M口腔脂质脂质中JP4-039的骨髓抑制
4. Antitumor activity of DACHPt-loaded polymeric micelles against a bioluminescent lung metastasis tumor model [C] . Horacio Cabral, Nobuhiro Noshiyama, Kazunori Kataoka Controlled Release Society Annual Meeting and Exposition . 2007

机译：负载DACHPt的聚合物胶束对生物发光肺转移肿瘤模型的抗肿瘤活性
5. Identification of surfactant protein B (SP-B) genomic regions required for lung-specific expression in transgenic mice. [D] . Adams, Constantin Claus. 2000

机译：鉴定在转基因小鼠中肺特异性表达所需的表面活性剂蛋白B（SP-B）基因组区域。
6. Driven by the same Ig enhancer and SV40 T promoter ras induced lung adenomatous tumors myc induced pre-B cell lymphomas and SV40 large T gene a variety of tumors in transgenic mice. [O] . Y Suda, S Aizawa, S Hirai, 1987

机译：在转基因小鼠中由相同的Ig增强剂和SV40 T启动子ras诱导的肺腺瘤肿瘤myc诱导的前B细胞淋巴瘤和SV40大T基因驱动了多种肿瘤。
7. Keratinocyte-specific stat3 heterozygosity impairs development of skin tumors in human papillomavirus 8 transgenic mice tumors in human papillomavirus 8 transgenic mice. [O] . De Andrea, Marco, Università Del Piemonte Orientale, Rittà, Massimo, 2010

机译：角质形成细胞特异性stat3杂合性损害人乳头瘤病毒8转基因小鼠的皮肤肿瘤的发展。
8. MUCI Facilitation of Growth in Chemically Induced Mammary Gland Tumors in Muc-1 Mutant and MUCI Transgenic Mice [R] . Gendler, S. 2000

机译：mU促进muc-1突变体和mUCI转基因小鼠中化学诱导的乳腺肿瘤的生长

Esophageal Radioprotection by Swallowed JP4-039/F15 in Thoracic-irradiated Mice with Transgenic Lung Tumors

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