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A randomized phase II study of bone-targeted therapy containing strontium-89 in advanced castrate-sensitive prostate cancer

机译：含锶89的骨靶向治疗在晚期去势敏感性前列腺癌中的随机II期研究

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摘要

BackgroundUse of radiopharmaceutical may improve the survival time of patients with castrate-resistant prostate cancer and bone metastases. Whether androgen-deprivation therapy (ADT) combined with bone-targeted therapy provides clinical benefit for patients with advanced castrate-sensitive prostate cancer has not been investigated.

机译：背景技术使用放射性药物可能会改善去势抵抗性前列腺癌和骨转移患者的生存时间。尚未研究雄激素剥夺疗法（ADT）与骨靶向疗法的结合是否对晚期去势敏感的前列腺癌患者提供临床益处。

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期刊名称 other
作者
Mehmet Asim Bilen; Marcella M. Johnson; Paul Mathew; Lance C. Pagliaro; John C. Araujo; Ana Aparicio; Paul G. Corn; Nizar M. Tannir; Franklin C. Wong; Michael J. Fisch; Christopher Logothetis; Shi-Ming Tu;
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年(卷),期 -1(121),1
年度 -1
页码 69–76
总页数 19
原文格式 PDF
正文语种
中图分类
关键词
Strontium-89 prostate cancer bone metastasis radiopharmaceutical phase-2;

机译：锶89;前列腺癌;骨转移;放射性药物;2期;

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专利

1. Randomized Phase 2 Study of Bone-Targeted Therapy Containing Strontium-89 in Advanced Castrate-Sensitive Prostate Cancer [J] . Bilen Mehmet Asim, Johnson Marcella M., Mathew Paul, Cancer: A Journal of the American Cancer Society . 2015,第1期

机译：含锶89的骨靶向疗法在晚期去势敏感型前列腺癌中的随机2期研究
2. Randomized Phase 2 Study of Bone-Targeted Therapy Containing Strontium-89 in Advanced Castrate-Sensitive Prostate Cancer [J] . Bilen Mehmet Asim, Johnson Marcella M., Mathew Paul, Cancer: A Journal of the American Cancer Society . 2015,第1期

机译：含有锶-89的骨靶向治疗在晚期阉割敏感前列腺癌中的随机阶段2研究
3. Bone-targeted therapy: phase II study of strontium-89 in combination with alternating weekly chemohormonal therapies for patients with advanced androgen-independent prostate cancer. [J] . Amato RJ, Hernandez-McClain J, Henary H American Journal of Clinical Oncology: Cancer Clinical Trials . 2008,第6期

机译：骨靶向疗法：锶89的II期研究与每周交替的化学激素疗法相结合，用于晚期雄激素非依赖性前列腺癌患者。
4. Vascular-Targeted Photodynamic of Prostate Cancer Phase with Tookad for Recurrent Prostate Cancer Following Radiation Therapy: Initial Clinical Studies [C] . Robert A. Weersink, Brian C. Wilson, Arjen Bogaards, Photonic Therapeutics and Diagnostics III; Progress in Biomedical Optics and Imaging; vol.8 no.1; Proceedings of SPIE-The International Society for Optical Engineering; vol.6424 . 2007

机译：Tookad用于前列腺癌放疗后复发性前列腺癌的血管靶向光动力学研究：初步临床研究
5. New Candidate Cancer Genes and Combination Therapy for Advanced Prostate Cancer. [D] . Le, Bao. 2017

机译：新的候选癌基因和晚期前列腺癌的联合治疗。
6. Patient‐reported outcomes following neoadjuvant endocrine therapy external beam radiation and adjuvant continuous/intermittent endocrine therapy for locally advanced prostate cancer: A randomized phase III trial [O] . Akira Yokomizo, Hirofumi Koga, Kazuto Ito, 2021

机译：患者报告的新辅助内分泌治疗后的结果外束辐射和佐剂连续/间歇内分泌治疗局部晚期前列腺癌：随机期III试验
7. Chemotherapy at first diagnosis of advanced prostate cancer – revolution or evolution? Findings from a British uro-oncology group UK survey to evaluate oncologists' views on first-line docetaxel in combination with androgen deprivation therapy in castrate-sensitive metastatic and high-risk/locally advanced prostate cancer [O] . Davda, R., Hughes, S., Jones, R., 2016

机译：首次诊断为晚期前列腺癌的化疗 - 革命还是进化？来自英国尿液肿瘤学组英国调查的结果，评估肿瘤学家对一线多西紫杉醇联合雄激素剥夺治疗对去势敏感的转移性和高风险/局部晚期前列腺癌的看法

A randomized phase II study of bone-targeted therapy containing strontium-89 in advanced castrate-sensitive prostate cancer

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