In Vivo Laser Cartilage Reshaping with Carbon Dioxide Spray Cooling in a Rabbit Ear Model: A Pilot Study

摘要

BACKGROUND/OBJECTIVESSimilar to conventional cryogen spray cooling, carbon dioxide (CO2) spray may be used in combination with laser cartilage reshaping (LCR) to produce cartilage shape change while minimizing cutaneous thermal injury. Recent ex vivo evaluation of LCR with CO2 cooling in a rabbit model has identified a promising initial parameter space for in vivo safety and efficacy evaluation. This pilot study aimed to evaluate shape change and cutaneous injury following LCR with CO2 cooling in 5 live rabbits.