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Allogeneic Cardiospheres Delivered via Percutaneous Transendocardial Injection Increase Viable Myocardium Decrease Scar Size and Attenuate Cardiac Dilatation in Porcine Ischemic Cardiomyopathy

机译：经皮心内膜内注射输送的同种异体心球可增加猪缺血性心肌病的存活心肌减少疤痕大小并减轻心肌扩张。

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BackgroundEpicardial injection of heart-derived cell products is safe and effective post-myocardial infarction (MI), but clinically-translatable transendocardial injection has never been evaluated. We sought to assess the feasibility, safety and efficacy of percutaneous transendocardial injection of heart-derived cells in porcine chronic ischemic cardiomyopathy.

机译：背景心脏源性细胞产品的心内膜注射是安全有效的心肌梗塞（MI），但从未对可临床翻译的心内膜注射进行过评估。我们试图评估在猪慢性缺血性心肌病中经皮心内膜注射心源性细胞的可行性，安全性和有效性。

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Kristine Yee; Konstantinos Malliaras; Hideaki Kanazawa; Eleni Tseliou; Ke Cheng; Daniel J. Luthringer; Chak-Sum Ho; Kentaro Takayama; Naoto Minamino; James F. Dawkins; Supurna Chowdhury; Doan Trang Duong; Jeffrey Seinfeld; Ryan C. Middleton; Rohan Dharmakumar; Debiao Li; Linda Marbán; Raj R. Makkar; Eduardo Marbán;
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年(卷),期 -1(9),12
年度 -1
页码 e113805
总页数 29
原文格式 PDF
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外文文献

1. Comparison of Allogeneic vs Autologous Bone Marrow-Derived Mesenchymal Stem Cells Delivered by Transendocardial Injection in Patients With Ischemic Cardiomyopathy The POSEIDON Randomized Trial [J] . Hare Joshua M., Fishman Joel E., Gerstenblith Gary, JAMA: the Journal of the American Medical Association . 2012,第22期

机译：经心内膜注射治疗缺血性心肌病患者异体和自体骨髓间充质干细胞的比较POSEIDON随机试验
2. Radio-guided surgery for ventricular remodeling in patients with ischemic dilated cardiomyopathy: a new tool to discriminate in vivo viable myocardium and scar. [J] . Spadafora M, Manganelli F, Mansi L The Journal of Thoracic and Cardiovascular Surgery . 2009,第1期

机译：放射性引导手术治疗缺血性扩张型心肌病患者的心室重塑：一种鉴别体内存活心肌和瘢痕的新工具。
3. Radio-guided surgery for ventricular remodeling in patients with ischemic dilated cardiomyopathy: A new tool to discriminate in vivo viable myocardium and scar [J] . Marco Spadafora, Fiore Manganelli, Luigi Mansi, The journal of thoracic and cardiovascular surgery . 2009,第1期

机译：放射性引导手术治疗缺血性扩张型心肌病患者的心室重构：鉴别体内存活心肌和瘢痕的新工具
4. Comparison of Allogeneic vs Autologous Bone Marrow–Derived Mesenchymal Stem Cells Delivered by Transendocardial Injection in Patients With Ischemic Cardiomyopathy [O] . Joshua M. Hare, Joel E. Fishman, Gary Gerstenblith, -1

机译：异体Vs自体骨髓比较间充质干在缺血性心肌病患由内膜注射交付细胞
5. Allogeneic cardiospheres delivered via percutaneous transendocardial injection increase viable myocardium, decrease scar size, and attenuate cardiac dilatation in porcine ischemic cardiomyopathy. [O] . Kristine Yee, Konstantinos Malliaras, Hideaki Kanazawa, 2014

机译：通过经皮经心内膜注射递送的同种异体心肌球增加存活心肌，减少瘢痕大小，并减弱猪缺血性心肌病的心脏扩张。

Allogeneic Cardiospheres Delivered via Percutaneous Transendocardial Injection Increase Viable Myocardium Decrease Scar Size and Attenuate Cardiac Dilatation in Porcine Ischemic Cardiomyopathy

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