Changes in Cellular Immune Activation and Memory T Cell Subsets in HIV-Infected Zambian Children Receiving HAART

摘要

BackgroundIncreased exposure to a broad array of pathogens in children residing in sub-Saharan Africa may lead to heightened immune activation and increased proportions of memory T cells. Changes in the size of these cellular subsets have implications for restoration of normal immune function after treatment with HAART and are not well-characterized in young sub-Saharan African children.