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Genetic Variants in Nitric Oxide Synthase Genes and the Risk of Male Infertility in a Chinese Population: A Case-Control Study

机译：一氧化氮合酶基因的遗传变异与中国人群男性不育的风险：病例对照研究

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BackgroundIn recent years, oxidative stress has been studied extensively as a main contributing factor to male infertility. Nitric Oxide, a highly reactive free radical gas, is potentially detrimental to sperm function and sperm DNA integrity at high levels. Thus, the aim of this study was to investigate the associations between five polymorphisms in nitric oxide synthase genes (NOSs) and the risk of male infertility and sperm DNA damage as well.

机译：背景技术近年来，氧化应激已被广泛研究为导致男性不育的主要因素。一氧化氮是一种高反应性的自由基气体，在高水平下可能对精子功能和精子DNA完整性有害。因此，本研究的目的是研究一氧化氮合酶基因（NOS）中的五个多态性与男性不育和精子DNA损伤的风险之间的关联。

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期刊名称 other
作者
Lifeng Yan; Wenhui Guo; Shengmin Wu; Jining Liu; Shenghu Zhang; Lili Shi; Guixiang Ji; Aihua Gu;
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年(卷),期 -1(9),12
年度 -1
页码 e115190
总页数 13
原文格式 PDF
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1. Functional Inducible Nitric Oxide Synthase Gene Variants Associate With Hypertension A Case-Control Study in a Finnish Population-The TAMRISK Study [J] . Nikkari Seppo T., Maeaettae Kirsi M., Kunnas Tarja A. Medicine. . 2015,第46期

机译：功能性诱导型一氧化氮合酶基因变体与高血压患者在芬兰人群中的案例对照研究 - Tamrisk研究
2. Investigation of the association of endothelial nitric oxide synthase (eNOS)-T786C gene polymorphism with the risk of male infertility in an Iranian population [J] . Environmental Science and Pollution Research . 2020,第18期

机译：内皮一氧化氮合酶（ENOS）-T786C基因多态性与伊朗人群男性不育症风险的研究
3. Genetic variants in antioxidant genes are associated with sperm DNA damage and risk of male infertility in a Chinese population [J] . JiG., GuA., WangY., Free Radical Biology and Medicine: The Official Journal of the Oxygen Society . 2012,第4期

机译：抗氧化剂基因的遗传变异与中国人口的精子DNA损伤和男性不育风险相关
4. Endothelial nitric oxide synthase gene polymorphisms and the risk of ischemic stroke in young Chinese population [C] . Congning Shi, Yajie Wang, Yali Zhou, International Forum on Progress on Post-Genome Technologies(5'IFPT); 20070910-11; Suzhou(CN) . 2007

机译：中国青年人内皮型一氧化氮合酶基因多态性与缺血性卒中的风险
5. Genetic Susceptibility and Environmental Risk Factors of Liver Cancer, a Population-based Case-control Study in Jiangsu Province, China. [D] . Liu, Xing. 2015

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6. Antioxidants-Related Superoxide Dismutase (SOD) Catalase (CAT) Glutathione Peroxidase (GPX) Glutathione-S-Transferase (GST) and Nitric Oxide Synthase (NOS) Gene Variants Analysis in an Obese Population: A Preliminary Case-Control Study [O] . Amani M. T. Gusti, Safaa Y. Qusti, Eida M. Alshammari, 2021

机译：抗氧化剂相关超氧化物歧化酶（SOD）过氧化氢酶（CAT）谷胱甘肽过氧化物酶（GPX）谷胱甘肽-S-转移酶（GST）和一氧化氮合酶（NOS）基因变体分析在肥胖群体中：初步案例对照研究
7. Genetic variants in nitric oxide synthase genes and the risk of male infertility in a Chinese population: a case-control study. [O] . Lifeng Yan, Wenhui Guo, Shengmin Wu, 2014

机译：一氧化氮合酶基因的遗传变异和中国人群中男性不育的风险：病例对照研究。

Genetic Variants in Nitric Oxide Synthase Genes and the Risk of Male Infertility in a Chinese Population: A Case-Control Study

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