Nanofibrous Hydrogels with Spatially Patterned Biochemical Signals to Control Cell Behavior

摘要

We demonstrate the ability to spatially pattern biochemical signals into nanofibrous materials using thiol-ene reactions of thiolated molecules to presented norbornene groups. This approach is used to pattern three molecules independently within one scaffold, pattern signals with depth through a scaffold, and to spatially control cell adhesion and morphology.