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Superficial Tunica Albuginea Rupture as Initial Starting Point of Peyronies Disease: A Topic for Interdisciplinary Consideration

机译:浅表皮膜白膜破裂作为佩罗尼氏病的初始起点:跨学科考虑的主题

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摘要

Peyronie's disease is a connective tissue disorder in the soft tissue of the penis. The underlying cause of Peyronie's disease is not well understood but is thought to be caused by trauma or injury to the penis during sexual intercourse. The purpose of the interdisciplinary cooperation between urological surgery and physics is the development of a physical simulation tool in order to give prognosis of possible tunica albuginea fibre rupture at a certain degree of deviation of the penis. For our group the first challenge was to translate the human organ of the penis into a physical model. Starting and marginal parameters had to be defined, whereby some of them had to be based on assumption, as physical data of the human living tissue have rarely been measured up to now. The algorithm and its dependencies had to be developed. This paper is a first step of a three-dimensional mathematical-physical simulation with the assumption of a 100% filled rigid penis. The calculation gives proof of the hypothesis that the fibre-load-angle of the penis is less than 12 degrees. Thus physical simulation is able to provide the surgeon with a simple instrument to calculate and forecast the risk of the individual patient.
机译:佩罗尼氏病是阴茎软组织中的结缔组织疾病。佩罗尼氏病的根本原因尚不清楚,但被认为是性交期间阴茎的外伤或受伤引起的。泌尿外科和物理学之间跨学科合作的目的是开发一种物理模拟工具,以便在阴茎偏离一定程度时预测白膜纤维破裂的预后。对于我们小组而言,第一个挑战是将阴茎的人体器官转化为物理模型。必须定义起始参数和边际参数,其中一些参数必须基于假设,因为到目前为止,人体活组织的物理数据很少被测量。该算法及其依赖项必须开发。本文是三维数学物理模拟的第一步,假设阴茎100%填充。该计算提供了以下假说的证据:阴茎的纤维负载角度小于12度。因此,物理模拟能够为外科医生提供一种简单的工具来计算和预测单个患者的风险。

著录项

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  • 作者

    Ralf Herwig; Manfred Bayerl;

  • 作者单位
  • 年(卷),期 -1(2015),-1
  • 年度 -1
  • 页码 751372
  • 总页数 7
  • 原文格式 PDF
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