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The Impact of Proposed Changes in Liver Allocation Policy on Cold Ischemia Times and Organ Transportation Costs

机译:肝脏分配策略的拟议变更对寒冷缺血时间和器官运输成本的影响

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Changes to the liver allocation system have been proposed to decrease regional variation in access to liver transplant. It is unclear what impact these changes will have on cold ischemia times (CITs) and donor transportation costs. Therefore, we performed a retrospective single center study (2008–2012) measuring liver procurement CIT and transportation costs. Four groups were defined: Local-within driving distance (Local-D, n = 262), Local-flight (Local-F, n = 105), Regional-flight <3 h (Regional <3h, n = 61) and Regional-Flight >3 h (Regional >3h, n = 53). The median travel distance increased in each group, varying from zero miles (Local-D), 196 miles (Local-F), 384 miles (Regional <3 h), to 1647 miles (Regional >3 h). Increasing travel distances did not significantly increase CIT until the flight time was >3 h. The average CIT ranged from 5.0 to 6.0 h for Local-D, Local-F and Regional <3h, but increased to 10 h for Regional >3h (p < 0.0001). Transportation costs increased with greater distance traveled: Local-D $101, Local-F $1993, Regional <3h $8324 and Regional >3 h $27 810 (p < 0.0001). With proposed redistricting, local financial modeling suggests that the average liver donor procurement transportation variable direct costs will increase from $2415 to $7547/liver donor, an increase of 313%. These findings suggest that further discussion among transplant centers and insurance providers is needed prior to policy implementation.
机译:已经提出改变肝脏分配系统以减少获得肝移植的区域差异。尚不清楚这些变化将对冷缺血时间(CIT)和供体运输成本产生什么影响。因此,我们进行了一项回顾性单中心研究(2008-2012年),该研究测量了肝脏采购的CIT和运输成本。定义了四组:本地驾驶距离内(Local-D,n = 262),本地飞行(Local-F,n = 105),区域飞行<3 h(区域<3h,n = 61)和区域-飞行> 3小时(区域> 3小时,n = 53)。每个组的中位旅行距离有所增加,从零英里(Local-D),196英里(Local-F),384英里(Regional <3 h)到1647英里(Regional> 3 h)。直到飞行时间> 3小时,增加的行驶距离才不会显着增加CIT。 Local-D,Local-F和Regional <3h的平均CIT范围为5.0到6.0小时,而Region> 3h的平均CIT则增加到10 h(p <0.0001)。运输成本随行进距离的增加而增加:Local-D $ 101,Local-F $ 1993,区域<3h $ 8324和区域> 3h $ 27,810(p <0.0001)。通过提议的重新划分,当地的财务模型表明,平均肝脏捐赠者采购运输可变直接成本将从2415美元增加到7547美元/肝脏捐赠者,增加313%。这些发现表明,在实施政策之前,需要在移植中心和保险提供商之间进行进一步的讨论。

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