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Recent Developments in Vascular Imaging Techniques in Tissue Engineering and Regenerative Medicine

机译:组织工程与再生医学中血管成像技术的最新进展

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摘要

Adequate vascularisation is key in determining the clinical outcome of stem cells and engineered tissue in regenerative medicine. Numerous imaging modalities have been developed and used for the visualization of vascularisation in tissue engineering. In this review, we briefly discuss the very recent advances aiming at high performance imaging of vasculature. We classify the vascular imaging modalities into three major groups: nonoptical methods (X-ray, magnetic resonance, ultrasound, and positron emission imaging), optical methods (optical coherence, fluorescence, multiphoton, and laser speckle imaging), and hybrid methods (photoacoustic imaging). We then summarize the strengths and challenges of these methods for preclinical and clinical applications.
机译:在再生医学中,充分的血管形成对于确定干细胞和工程组织的临床结果至关重要。已经开发了多种成像方式并将其用于组织工程中血管化的可视化。在这篇综述中,我们简要讨论了针对脉管系统高性能成像的最新进展。我们将血管成像方式分为三大类:非光学方法(X射线,磁共振,超声和正电子发射成像),光学方法(光学相干,荧光,多光子和激光散斑成像)和混合方法(光声)成像)。然后,我们总结了这些方法在临床前和临床应用中的优势和挑战。

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