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The Effect of Daily Co-Trimoxazole Prophylaxis on Natural Development of Antibody-Mediated Immunity against P. falciparum Malaria Infection in HIV-Exposed Uninfected Malawian Children

机译：每天接受三苯恶唑预防对HIV感染未感染马拉维儿童的恶性疟原虫疟疾感染抗体介导的免疫的自然发育的影响。

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Background and ObjectivesCo-trimoxazole prophylaxis, currently recommended in HIV-exposed, uninfected (HEU) children as protection against opportunistic infections, also has some anti-malarial efficacy. We determined whether daily co-trimoxazole prophylaxis affects the natural development of antibody-mediated immunity to blood-stage Plasmodium falciparum malaria infection.

机译：背景和目的目前建议在暴露于HIV的未感染（HEU）儿童中预防使用复方新诺明以预防机会感染，它也具有一定的抗疟疾功效。我们确定了每天的复方新诺明预防措施是否会影响抗体介导的针对血液阶段恶性疟原虫疟疾感染的免疫力的自然发育。

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期刊名称 other
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Herbert Longwe; Kondwani C. Jambo; Kamija S. Phiri; Nyanyiwe Mbeye; Thandile Gondwe; Tom Hall; Kevin K. A. Tetteh; Chris Drakeley; Wilson L. Mandala;
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年(卷),期 -1(10),3
年度 -1
页码 e0121643
总页数 16
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专利

1. The impact of early life exposure to Plasmodium falciparum on the development of naturally acquired immunity to malaria in young Malawian children [J] . Priyanka Barua, James G. Beeson, Kenneth Maleta, Malaria Journal . 2019,第1期

机译：早期接触恶性疟原虫对马拉维幼儿童自然获得的抗疟疾免疫力发展的影响
2. The Effect of Frequent Exposure to P. falciparum , HIV-Infection and Other Co-Morbidities on Development of Severe Malaria in Malawian Adults [J] . Alinane U Munyenyembe, Kamunkhwala Gausi, Jasmin Hiestand, Infection and Drug Resistance . 2020,第1期

机译：频繁暴露于P. falciparum，HIV感染等持续处理对马拉维成人严重疟疾的影响的影响
3. Protective efficacy of prolonged co-trimoxazole prophylaxis in HIV-exposed children up to age 4 years for the prevention of malaria in Uganda: a randomised controlled open-label trial [J] . Jaco Homsy, Grant Dorsey, Emmanuel Arinaitwe, The Lancet Global Health . 2014,第12期

机译：延长预防性复方新诺明在4岁以下感染HIV的儿童中预防乌干达疟疾的保护作用：一项随机对照开放标签试验
4. Development and Immunopathologic Characterization of SIV- Plasmodium fragile Co-Infection in the Rhesus Macaque as a Model for HIV and P. falciparum Co-Infection in Humans [D] . Trott, Kristin A. 2012

机译：作为人类HIV和恶性疟原虫共感染的模型，恒河猴中SIV-脆弱性疟原虫共感染的发展和免疫病理学特征
5. Delayed acquisition of Plasmodium falciparum antigen-specific CD4+ T cell responses in HIV-exposed uninfected Malawian children receiving daily cotrimoxazole prophylaxis [O] . Herbert Longwe, Kamija S. Phiri, Nyanyiwe M. Mbeye, 2016

机译：每天接受cotrimoxazole预防的暴露于HIV的未感染马拉维儿童中延迟获取恶性疟原虫抗原特异性CD4 + T细胞应答
6. The effect of daily co-trimoxazole prophylaxis on natural development of antibody-mediated immunity against P. falciparum malaria infection in HIV-exposed uninfected Malawian children. [O] . Herbert Longwe, Kondwani C Jambo, Kamija S Phiri, 2015

机译：每日复方新诺明预防对HIV暴露的未感染马拉维儿童抗体介导的抗恶性疟原虫感染免疫的自然发展的影响。
7. Red Blood Cell Immune Complex Binding Capacity in Children with Sickle Cell Trait (HbAS) Living in P. falciparum Malaria Holoendemic Region of Western Kenya. [R] . Otieno, W., Estambale, B. B., Odera, M. M., 2012

机译：镰状细胞性状（Hbas）患儿的红细胞免疫复合物结合能力生活在肯尼亚西部的恶性疟原虫全流行区。

The Effect of Daily Co-Trimoxazole Prophylaxis on Natural Development of Antibody-Mediated Immunity against P. falciparum Malaria Infection in HIV-Exposed Uninfected Malawian Children

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