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Adjuvant exemestane versus tamoxifen in premenopausal women with early breast cancer undergoing ovarian suppression: patient-reported outcomes in the TEXT and SOFT randomised trials

机译：依西美坦与他莫昔芬的辅助治疗在患有卵巢抑制的绝经前早期乳腺癌患者中：TEXT和SOFT随机试验中患者报告的结果

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BackgroundEfficacy analysis of the combined IBCSG TEXT and SOFT trials showed a significant disease-free survival benefit for exemestane plus ovarian function suppression (OFS) compared with tamoxifen +OFS. We present patient-reported outcomes from these trials.

机译：背景IBCSG TEXT和SOFT联合试验的功效分析显示，与他莫昔芬+ OFS相比，依西美坦和卵巢功能抑制（OFS）的无病生存获益显着。我们介绍了这些试验中患者报告的结果。

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期刊名称 other
作者
Jürg Bernhard; Weixiu Luo; Karin Ribi; Marco Colleoni; Harold J. Burstein; Carlo Tondini; Graziella Pinotti; Simon Spazzapan; Thomas Ruhstaller; Fabio Puglisi; Lorenzo Pavesi; Vani Parmar; Meredith M. Regan; Olivia Pagani; Gini F. Fleming; Prudence A. Francis; Karen N. Price; Alan S. Coates; Richard D. Gelber; Aron Goldhirsch; Barbara A. Walley;
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年(卷),期 -1(16),7
年度 -1
页码 848–858
总页数 23
原文格式 PDF
正文语种
中图分类
关键词
adjuvant therapy aromatase inhibitor breast cancer endocrine therapy exemestane GnRH agonist ovarian function suppression premenopausal quality of life sexual functioning tamoxifen triptorelin;

机译：辅助疗法;芳香酶抑制剂;乳腺癌;内分泌疗法;依西美坦;GnRH激动剂;卵巢功能抑制;绝经前;生活质量;性功能;他莫昔芬;曲普瑞林;

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专利

1. Patient-reported outcomes with adjuvant exemestane versus tamoxifen in premenopausal women with early breast cancer undergoing ovarian suppression (TEXT and SOFT): a combined analysis of two phase 3 randomised trials [J] . Bernhard Juerg, Luo Weixiu, Ribi Karin, The lancet oncology . 2015,第7期

机译：患者报告的依西美坦与他莫昔芬辅助治疗在患有卵巢抑制的绝经前早期乳腺癌患者中的疗效（TEXT和SOFT）：两项3期随机试验的综合分析
2. Adjuvant Tamoxifen Plus Ovarian Function Suppression Versus Tamoxifen Alone in Premenopausal Women With Early Breast Cancer: Patient-Reported Outcomes in the Suppression of Ovarian Function Trial [J] . Ribi Karin, Luo Weixiu, Bernhard Jurg, Journal of Clinical Oncology . 2016,第14期

机译：在早期乳腺癌的绝经前妇女中，辅助用药他莫昔芬加卵巢功能抑制与单独使用他莫昔芬相比：患者报告的抑制卵巢功能试验的结果
3. Twelve-Month Estrogen Levels in Premenopausal Women With Hormone Receptor-Positive Breast Cancer Receiving Adjuvant Triptorelin Plus Exemestane or Tamoxifen in the Suppression of Ovarian Function Trial (SOFT): The SOFT-EST Substudy [J] . Bellet Meritxell, Gray Kathryn P., Francis Prudence A., Journal of Clinical Oncology . 2016,第14期

机译：激素受体阳性乳腺癌的绝经前妇女在抑制卵巢功能试验中接受曲普瑞林加依西美坦或他莫昔芬辅助治疗的十二个月雌激素水平（SOFT）：SOFT-EST子研究
4. Dietary associations with biomarkers of breast cancer risk in women on adjuvant tamoxifen therapy. [D] . Strom, Meghan Brianna. 2016

机译：辅助性他莫昔芬治疗妇女饮食中与乳腺癌风险生物标志物的关联。
5. Adjuvant Tamoxifen Plus Ovarian Function Suppression Versus Tamoxifen Alone in Premenopausal Women With Early Breast Cancer: Patient-Reported Outcomes in the Suppression of Ovarian Function Trial [O] . Karin Ribi, Weixiu Luo, Jürg Bernhard, -1

机译：辅助性他莫昔芬加卵巢功能抑制与单独使用他莫昔芬相比早期乳腺癌的绝经前妇女：患者报告的卵巢功能抑制试验结果
6. Patient-reported outcomes with adjuvant exemestane versus tamoxifen in premenopausal women with early breast cancer undergoing ovarian suppression (TEXT and SOFT): a combined analysis of two phase 3 randomised trials [O] . Bernhard, Jürg, Luo, Weixiu, Pavesi, Lorenzo, 2015

机译：患者报告的依西美坦与他莫昔芬辅助治疗在患有卵巢抑制的绝经前早期乳腺癌患者中的疗效（TEXT和SOFT）：两项3期随机试验的综合分析

Adjuvant exemestane versus tamoxifen in premenopausal women with early breast cancer undergoing ovarian suppression: patient-reported outcomes in the TEXT and SOFT randomised trials

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